Hiv-1 10-mer tar rna containing 2'-o-methyl and 2',4'-locked nucleotides: [5'-lna(c)-2'-ome(u)-lna(c)-2'-ome(c)-lna(c)-2'-ome(a)-2'-ome(g)-2'-ome(g)-lna(c)-2'-ome(u)-l-homoserine-6-carboxyfluorescein]

Structural Information

Molecular Formula

C₁₃₂H₁₅₈N₃₆O₇₉P₁₀

SMILES

CC1=CN(C(=O)N=C1N)C2C3C(C(O2)(CO3)CO)OP(=O)(O)OCC4C(C(C(O4)N5C=CC(=O)NC5=O)OC)OP(=O)(O)OCC67COC(C6OP(=O)(O)OCC8C(C(C(O8)N9C=CC(=NC9=O)N)OC)OP(=O)(O)OCC12COC(C1OP(=O)(O)OCC1C(C(C(O1)N1C=NC3=C(N=CN=C31)N)OC)OP(=O)(O)OCC1C(C(C(O1)N1C=NC3=C1N=C(NC3=O)N)OC)OP(=O)(O)OCC1C(C(C(O1)N1C=NC3=C1N=C(NC3=O)N)OC)OP(=O)(O)OCC13COC(C1OP(=O)(O)OCC1C(C(C(O1)N1C=CC(=O)NC1=O)OC)OP(=O)(O)OCC[C@@H](C(=O)N)NC(=O)C1=CC4=C(C=C1)C(=O)OC41C4=C(C=C(C=C4)O)OC4=C1C=CC(=C4)O)C(O3)N1C=C(C(=NC1=O)N)C)C(O2)N1C=C(C(=NC1=O)N)C)C(O7)N1C=C(C(=NC1=O)N)C

InChI

InChI=1S/C132H158N36O79P10/c1-50-28-162(124(182)151-96(50)134)114-88-92(128(38-169,233-114)39-212-88)244-251(192,193)219-35-66-78(84(208-7)110(229-66)161-23-19-72(173)150-123(161)181)242-256(202,203)224-44-129-40-213-89(115(234-129)163-29-51(2)97(135)152-125(163)183)93(129)246-253(196,197)221-36-65-77(83(207-6)108(227-65)159-21-17-70(133)148-121(159)179)241-255(200,201)223-43-130-41-214-91(117(235-130)165-31-53(4)99(137)154-127(165)185)95(130)247-254(198,199)222-37-69-79(85(209-8)111(230-69)166-47-144-73-100(138)142-46-143-102(73)166)239-249(188,189)217-32-67-80(86(210-9)112(231-67)167-48-145-74-103(167)155-119(140)157-106(74)176)240-250(190,191)218-33-68-81(87(211-10)113(232-68)168-49-146-75-104(168)156-120(141)158-107(75)177)243-257(204,205)225-45-131-42-215-90(116(236-131)164-30-52(3)98(136)153-126(164)184)94(131)245-252(194,195)220-34-64-76(82(206-5)109(228-64)160-22-18-71(172)149-122(160)180)238-248(186,187)216-24-20-61(101(139)174)147-105(175)54-11-14-57-60(25-54)132(237-118(57)178)58-15-12-55(170)26-62(58)226-63-27-56(171)13-16-59(63)132/h11-19,21-23,25-31,46-49,61,64-69,76-95,108-117,169-171H,20,24,32-45H2,1-10H3,(H2,139,174)(H,147,175)(H,186,187)(H,188,189)(H,190,191)(H,192,193)(H,194,195)(H,196,197)(H,198,199)(H,200,201)(H,202,203)(H,204,205)(H2,133,148,179)(H2,134,151,182)(H2,135,152,183)(H2,136,153,184)(H2,137,154,185)(H2,138,142,143)(H,149,172,180)(H,150,173,181)(H3,140,155,157,176)(H3,141,156,158,177)/t61-,64?,65?,66?,67?,68?,69?,76?,77?,78?,79?,80?,81?,82?,83?,84?,85?,86?,87?,88?,89?,90?,91?,92?,93?,94?,95?,108?,109?,110?,111?,112?,113?,114?,115?,116?,117?,128?,129?,130?,131?/m0/s1

InChIKey

ORHRFMNCOKALSJ-GAAAPEHVSA-N

Compound name

[3-[[7-[[3-[[7-[[3-[[3-[[3-[[7-[[3-[[(3S)-4-amino-3-[(3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carbonyl)amino]-4-oxobutoxy]-hydroxyphosphoryl]oxy-5-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphoryl]oxy-5-(2-amino-6-oxo-1H-purin-9-yl)-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(2-amino-6-oxo-1H-purin-9-yl)-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphoryl]oxy-5-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-2-yl]methyl [3-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl] hydrogen phosphate

Related CIDs

• CID 16131958